Origins

The Story of Adult Stem Cells
by Christian Drapeau, MSc.
EMBRYONIC stem
cells (ESC) have been in the news since 1998 when stem cells
obtained from a human embryo were first successfully grown in
vitro. And as ESC were shown to have the ability of becoming
virtually any cell type of the body, this achievment inspired
many promises and raised much expectation. Could injection of
ESC lead to improvements in various degenerative diseases? Would
it be possible to grow organs in vitro for the purpose of transplant?
Could we manipulate the genetic material of embryonic stem cells
in order to repair faulty genes in an organ?
Adult stem cells... were also shown to have the ability of becoming
virtually any cell type of the body.
But as ESC were fueling much hope, research with ESC became
rapidly encumbered by serious ethical considerations. First,
the source of human ESC has to be human embryos. The idea of
growing human embryos with the intent of dismembering them after
a week or so in order to grow ESC is obviously questionable.
Second and more worrisome is the fact that culturing human ESC
could open the door to human cloning in order to grow actual
organs. But aside from these ethical issues, the main issue
is that in spite of all the promises of ESC research, nearly
10 years of research have delivered little in terms of successful
and safe ESC-based therapeutic approach.
But, while much of the world focused on developments in ESC
research, another breakthrough discovery was being made by numerous
scientific teams throughout the world. Adult stem cells (ASC),
the stem cells present in the body after birth, were also shown
to have the ability of becoming virtually any cell type of the
body. ASC placed on brain, liver or muscle tissue will rapidly
become brain, liver and muscle cells. At first, because ASC
are difficult to grow in vitro, many believed that they had
little potential, but a series of in vivo studies rapidly established
that ASC have enormous potential in the body.
This discovery then spurred the concept that adult stem cells,
having the ability of becoming any cell type of the body, might
constitute the natural renewal sytem of the body. Studies using
various novel scientific tools like Green Fluorescent Protein,
which allows visual tracking of stem cells in the body, showed
that when an organ is challenged it causes the release of compounds
known to trigger stem cell release from the bone marrow. The
organ then releases compounds known to attract stem cells, and
the released stem cells travel to that organ. As they reach
the organ in need, the stem cells migrate in the organ, proliferate
and become cells of that organ, promoting tissue renewal.
This process takes place every day of our lives, and constitutes
the natural innate renewal sytem of the body. As stem cells
travel in the body, they participate in maintaining optimal
health throughout the body.
Christian Drapeau MSc, is the Chief Science Officer of StemTech
Health Sciences, Inc. and co-inventor and patent holder of StemEnhance,
the world's first natural stem cell enhancer.